The expression and functional analysis of the sialyl-T antigen in prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-020-09927-x
Abstract: Aberrant glycosylation is a featured characteristic of cancer and plays a role in cancer pathology; thus an understanding of the compositions and functions of glycans is critical for discovering diagnostic biomarkers and therapeutic targets for… read more here.
Keywords: cancer; analysis; prostate cancer; sialyl antigen ... See more keywords
Differential Distribution of N- and O-Glycans and Variable Expression of Sialyl-T Antigen on HeLa Cells-Revealed by Direct Fluorescent Glycan Imaging.
Sign Up to like & getrecommendations! Published in 2020 at "Glycobiology"
DOI: 10.1093/glycob/cwz110
Abstract: Cells are covered with glycans. The expression and distribution of specific glycans on the surface of a cell are important for various cellular functions. Imaging these glycans is essential to aid elucidation of their biological… read more here.
Keywords: distribution glycans; differential distribution; expression; direct fluorescent ... See more keywords
Mucin-type sialyl-Tn antigen is associated with PD-L1 expression and predicts poor clinical prognosis in breast cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Gland surgery"
DOI: 10.21037/gs-21-83
Abstract: Background A recent study showed that mucin-type sialylated O-linked glycans could induce the increased expression of PD-L1 via binding to Siglec receptors. However, the relationship between the expression of the mucin-type sialyl-Tn antigen (sTn) and… read more here.
Keywords: stn expression; mucin type; type sialyl; expression ... See more keywords
The (Sialyl) Tn antigen: Contributions to immunosuppression in gastrointestinal cancers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1093496
Abstract: Cellular signaling pathways are intricately regulated to maintain homeostasis. During cancer progression, these mechanisms are manipulated to become harmful. O-glycosylation, a crucial post-translational modification, is one such pathway that can lead to multiple isoforms of… read more here.
Keywords: sialyl antigen; contributions immunosuppression; gastrointestinal cancers; antigen contributions ... See more keywords