Active‐Site His85 of Pasteurella dagmatis Sialyltransferase Facilitates Productive Sialyl Transfer and So Prevents Futile Hydrolysis of CMP‐Neu5Ac
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DOI: 10.1002/cbic.201700113
Abstract: Sialyltransferases of the GT‐80 glycosyltransferase family are considered multifunctional because of the array of activities detected. They exhibit glycosyl transfer, trans‐sialylation, and hydrolysis activities. How these enzymes utilize their active‐site residues in balancing the different… read more here.
Keywords: cmp neu5ac; sialyl transfer; site; hydrolysis ... See more keywords