Erythrocyte ATP, a possible therapeutic approach for sickle cell disease
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25419
Abstract: This letter presents some suggestions of possible therapies for sickle cell disease that are based on interpretations of presumed effects of different substrates that alter the cellular levels of ATP. A prevailing idea is that… read more here.
Keywords: atp; pyruvate; cell disease; sickle ... See more keywords
Voxelotor in sickle cell disease
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26549
Abstract: A 45-year-old woman with sickle cell/ß thalassemia due to the HBB :c.92 + 5G>C severe ß + thalassemia mutation, who had been on a clinical trial of voxelotor for 4 years was assessed clinically and… read more here.
Keywords: cell; voxelotor; sickle; cell disease ... See more keywords
An integrated therapeutic approach to sickle cell disease management beyond infancy.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of hematology"
DOI: 10.1002/ajh.26956
Abstract: Hydroxyurea, the first approved drug for sickle cell disease, decreases sickle hemoglobin polymerization by inducing fetal hemoglobin. Its effects in young children are excellent; responses in adults are variable and not curative. The goal of… read more here.
Keywords: cell disease; sickle; sickle cell; sickle hemoglobin ... See more keywords
Development of 3D Intelligent Quantitative Phase Microscope for Sickle Cells Screening
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202400512
Abstract: Sickle cell disease (SCD) is a genetic blood disorder causing red blood cells to deform into a sickle shape, often leading to misdiagnosis. Early detection is crucial, but traditional screening is slow and labor‐intensive. This… read more here.
Keywords: system; development intelligent; microscope; intelligent quantitative ... See more keywords
Validity of simple clinical and biological parameters as screening tool for sickle cell anemia for referral to tertiary center in highly resource constraints
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22145
Abstract: In the Democratic Republic of Congo, the incidence of sickle cell anemia (SCA) is estimated around 40 000 neonates per year. However, it is notoriously difficult to perform conventional electrophoresis in all hospitals and laboratories,… read more here.
Keywords: highly resource; validity simple; cell anemia; sickle ... See more keywords
Sickle cell retinopathy. A focused review
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04294-2
Abstract: PurposeTo provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of… read more here.
Keywords: retinopathy; sickle; sickle cell; focused review ... See more keywords
Chronically Happy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of General Internal Medicine"
DOI: 10.1007/s11606-018-4684-3
Abstract: M y earliest memory of having sickle cell was in second grade. It was my first case of acute chest. I was hospitalized for a week, the longest I had ever been admitted. I remember… read more here.
Keywords: time; day; sickle; sickle cell ... See more keywords
Spontaneous splenic rupture, mesenteric ischemia and spinal infarction after aortic repair for acute type A dissection in a patient with sickle cell trait
Sign Up to like & getrecommendations! Published in 2020 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-020-01520-1
Abstract: Sickle cell trait (SCT), a benign hematological condition affecting approximately 300 million individuals globally, is associated with an increased risk of vaso-occlusive disease. However, the risks related to surgery employing cardiopulmonary bypass in patients with… read more here.
Keywords: aortic repair; cell trait; infarction; sickle ... See more keywords
Review/overview of pain in sickle cell disease.
Sign Up to like & getrecommendations! Published in 2020 at "Complementary therapies in medicine"
DOI: 10.1016/j.ctim.2020.102327
Abstract: Sickle cell disease (SCD) is a highly complex inherited disorder of hemoglobin structure. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing multiple phenotypic expressions that constitute the… read more here.
Keywords: cell disease; review; sickle; cell ... See more keywords
A positive correlation between sickle cell anemia and g6pd deficiency from population of Chhattisgarh, India.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.04.080
Abstract: OBJECTIVE Present study was undertaken to study the association between sickle cell anemia (SCA) and glucose-6-phosphate dehydrogenase (G6PD) deficiency from Sahu and Kurmi population of Durg and Rajnandgaon district of Chhattisgarh, India. METHOD A random… read more here.
Keywords: g6pd; positive correlation; g6pd deficiency; sickle ... See more keywords
Sickle Hepatopathy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical and experimental hepatology"
DOI: 10.1016/j.jceh.2020.08.003
Abstract: Sickle hepatopathy is an umbrella term describing various pattern of liver injury seen in patients with sickle cell disease. The disease is not uncommon in India; in terms of prevalence, India is second only to… read more here.
Keywords: sickle hepatopathy; disease; cell disease; sickle ... See more keywords