Association of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.2141
Abstract: Importance Sickle cell trait (SCT), defined as the presence of 1 hemoglobin beta sickle allele (rs334-T) and 1 normal beta allele, is prevalent in millions of people in the US, particularly in individuals of African… read more here.
Keywords: cell trait; acute kidney; kidney; association ... See more keywords
Lactated Ringer vs Normal Saline Solution During Sickle Cell Vaso-Occlusive Episodes.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2024.4428
Abstract: Importance Sickle cell disease (SCD), a clinically heterogenous genetic hemoglobinopathy, is characterized by painful vaso-occlusive episodes (VOEs) that can require hospitalization. Patients admitted with VOEs are often initially resuscitated with normal saline (NS) to improve… read more here.
Keywords: lactated ringer; normal saline; occlusive episodes; sickle cell ... See more keywords
Severe Maternal Morbidity and Mortality in Sickle Cell Disease in the National Inpatient Sample, 2012-2018
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.54552
Abstract: Key Points Question What are the rates of and risks for severe maternal morbidity (SMM) among birthing people with sickle cell disease (SCD), and what proportion of the increased risk for adverse pregnancy outcomes in… read more here.
Keywords: people scd; deliveries among; severe maternal; maternal morbidity ... See more keywords
Changes in Hydroxyurea Use Among Youths Enrolled in Medicaid With Sickle Cell Anemia After 2014 Revision of Clinical Guidelines.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2023.4584
Abstract: Importance Youths with sickle cell anemia (SCA) are at risk of pain crises, stroke, and early death. Complications can be reduced by the oral disease-modifying medication hydroxyurea, and in 2014, the National Heart, Lung, and… read more here.
Keywords: cell anemia; changes hydroxyurea; use; among youths ... See more keywords
COVID-19 Immunization Coverage Among People With Sickle Cell Disease
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.51618
Abstract: This cross-sectional study compares the completion of the primary COVID-19 vaccine series in Michigan residents with vs without sickle cell disease and by age group. read more here.
Keywords: immunization coverage; cell disease; sickle cell; covid immunization ... See more keywords
Sickle Cell Disease and Dental Care Access Among Medicaid-Enrolled Youths
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.29849
Abstract: This cross-sectional study compares receipt of dental care among youths with and without sickle cell disease in Michigan. read more here.
Keywords: cell disease; sickle cell; dental care;
Hope, Hype, and Trust in Sickle Cell Disease.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2025.4749
Abstract: This Viewpoint discusses how to communicate trust for novel rare disease treatments using lessons learned from sickle cell disease. read more here.
Keywords: disease; cell disease; sickle cell; trust ... See more keywords
Systematic online academic resources (SOAR) review: Sickle cell disorders
Sign Up to like & getrecommendations! Published in 2022 at "AEM Education and Training"
DOI: 10.1002/aet2.10812
Abstract: Free open‐access medical education (FOAM) resources have become highly utilized resources in emergency medicine education. However, FOAM content often lacks the traditional peer review process, leaving quality assessment to the readers. In this systematic online… read more here.
Keywords: online academic; review; systematic online; soar review ... See more keywords
Acute pain in adolescents and young adults with sickle cell disease: Delayed and increased opioid dosing following transition to adult care
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24647
Abstract: The transition from pediatric to adult care is a high risk time for adolescent and young adult (AYA) patients with sickle cell disease (SCD). Management of acute pain is a major point of contact between… read more here.
Keywords: adult; transition; adult care; cell disease ... See more keywords
The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso‐occlusive crises
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24750
Abstract: Sickle Cell Disease (SCD) is a painful, lifelong hemoglobinopathy inherited as a missense point mutation in the hemoglobin (Hb) beta‐globin gene. This disease has significant impact on quality of life and mortality, thus a substantial… read more here.
Keywords: occlusive crises; heme; vaso occlusive; disease ... See more keywords
Losartan for the nephropathy of sickle cell anemia: A phase‐2, multicenter trial
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24810
Abstract: Nephropathy is a common and progressive complication of sickle cell anemia (SCA). In SCA mice, we found that hyperangiotensinemia in the absence of hypertension underlies nephropathy, and its downregulation by losartan, an angiotensin‐II‐receptor‐1 blocker, reduced… read more here.
Keywords: trial; losartan nephropathy; losartan; cell anemia ... See more keywords