Sickling-preventive effects of rutin is associated with modulation of deoxygenated haemoglobin, 2,3-bisphosphoglycerate mutase, redox status and alteration of functional chemistry in sickle erythrocytes
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DOI: 10.1016/j.heliyon.2019.e01905
Abstract: Sickle cell anaemia is a hereditary disease branded by an upsurge in generation of ROS, irregular iron release and little or no antioxidant activity which can lead to cellular injuries due to oxidative stress resulting… read more here.
Keywords: haemoglobin bisphosphoglycerate; effects rutin; bisphosphoglycerate mutase; chemistry ... See more keywords
Antioxidant properties and membrane stabilization effects of methanol extract of Mucuna pruriens leaves on normal and sickle erythrocytes
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DOI: 10.1016/j.jtcme.2017.08.002
Abstract: This study was aimed at investigating the antioxidant properties and membrane stabilization effects of Mucuna pruriens leaves on sickle erythrocyte as a possible means of sickle cell disease management. Pulverized plant material was extracted with… read more here.
Keywords: sickle erythrocytes; normal sickle; stabilization; antioxidant properties ... See more keywords