Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases
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DOI: 10.1126/science.aaw7446
Abstract: Divergent protein kinase SidJ is a protein produced by Legionella pneumophila that orchestrates this intracellular pathogen's establishment within the host cell. SidJ prevents lysosome fusion with the vacuole, within which the bacterium resides and replicates.… read more here.
Keywords: family ubiquitin; ubiquitin ligases; polyglutamylation; host ... See more keywords