Isolation of Cancer Stem Cells by Side Population Method.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7401-6_5
Abstract: The Hoechst side population (SP) method is a flow cytometry technique used to obtain stem cells based on the dye efflux properties of the ATP-binding cassette (ABC) transporters. The SP cells are characterized by their… read more here.
Keywords: side population; cancer stem; population method; method ... See more keywords
MicroRNA-194 inhibits PRC1 activation of the Wnt/β-catenin signaling pathway to prevent tumorigenesis by elevating self-renewal of non-side population cells and side population cells in esophageal cancer stem cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03412-z
Abstract: Esophageal cancer (EC) is a leading cause of cancer-related deaths worldwide. Recent studies highlight roles for microRNAs (miRNAs) in EC. Microarray analysis identified miR-194 as downregulated in EC. However, little is known about the role… read more here.
Keywords: side population; catenin signaling; signaling pathway; stem cells ... See more keywords
Distinct Side Population Cell Subtypes Have Different Stemness Levels in Human Ovarian Cancer Cells
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DOI: 10.1007/s11596-021-2327-0
Abstract: The stemness of different side population (SP) cell subtypes in ovarian cancer cells was studied, and the heterogeneity of ovarian cancer stem cells was analyzed. The cisplatin-resistant human serous ovarian cancer cell line C13 was… read more here.
Keywords: side population; cell subtypes; ovarian cancer; cancer cells ... See more keywords
Circulatory shear stress induces molecular changes and side population enrichment in primary tumor-derived lung cancer cells with higher metastatic potential
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82634-1
Abstract: Cancer is a leading cause of death and disease worldwide. However, while the survival for patients with primary cancers is improving, the ability to prevent metastatic cancer has not. Once patients develop metastases, their prognosis… read more here.
Keywords: side population; molecular changes; circulatory; cancer cells ... See more keywords
Bortezomib Is More Effective to Side Population of RPMI8226 Myeloma Cells than Classical Anti-myeloma Agents
Sign Up to like & getrecommendations! Published in 2018 at "AntiCancer Research"
DOI: 10.21873/anticanres.13088
Abstract: Aim: Cytotoxic chemotherapy-based treatment of multiple myeloma (MM) is not curative, and the disease eventually recurs. This is partially because although currently available anti-MM strategies are effective in targeting the bulk of tumor cells, they… read more here.
Keywords: side population; myeloma; myeloma cells; population ... See more keywords
Fms-like tyrosine kinase 3 is a regulator of the cardiac side population in mice
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DOI: 10.26508/lsa.202101112
Abstract: This work shows that Flt3 signaling regulates the composition and functionality of the cardiac side population, which could be relevant for cardiovascular homeostasis under Flt3-inhibitory therapies. Fms-like tyrosine kinase 3 (Flt3) is a regulator of… read more here.
Keywords: kinase; tyrosine kinase; side population; cardiac side ... See more keywords
Hypoxia-Driven TGFβ Modulation of Side Population Cells in Breast Cancer: The Potential Role of ERα
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DOI: 10.3390/cancers15041108
Abstract: Simple Summary A process termed epithelial-to-mesenchymal transition can allow cancer cells to acquire or increase stem cell-like characteristics, which include increased potentials for migration and tissue invasion. This study focused on the effects of transforming… read more here.
Keywords: cell; population cells; breast cancer; side population ... See more keywords
sATP-binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Reports"
DOI: 10.3892/or.2020.7722
Abstract: Extranodal natural killer (NK)/T cell lymphoma, nasal type (ENKL) is a rare type of non-Hodgkin's lymphoma that is associated with limited effective treatment options and unfavorable survival rate, which is partly the result of multidrug… read more here.
Keywords: side population; killer cell; natural killer; resistance ... See more keywords