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   Articles with "sidedness" as a keyword



Primary tumor sidedness and benefit from FOLFOXIRI plus bevacizumab as initial therapy for metastatic colorectal cancer. Retrospective analysis of the TRIBE trial by GONO

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recommendations! Published in 2018 at "Annals of Oncology"

DOI: 10.1093/annonc/mdy140

Abstract: Background Right-sided metastatic colorectal cancer (mCRC) patients have poor prognosis and achieve limited benefit from first-line doublets plus a targeted agent. In this unplanned analysis of the TRIBE study, we investigated the prognostic and predictive… read more here.

Keywords: status; sidedness; metastatic colorectal; plus bevacizumab ... See more keywords

The role of sidedness, EGFR gene copy number (GCN) and EGFR promoter methylation in RAS/BRAF wild type (WT) colorectal cancer (CRC) patients receiving irinotecan/cetuximab.

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recommendations! Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.4_suppl.628

Abstract: 628Background: Data from randomized trials suggested that tumour sidedness could represent a prognostic and predictive factor in CRC patients. Distinctive molecular and clinical features are related to tumour sidedness, however their predictive role has not… read more here.

Keywords: sidedness; egfr promoter; promoter methylation; crc patients ... See more keywords

Impact of primary tumor sidedness on survival after resection of colorectal liver metastases (CRLM).

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recommendations! Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.4_suppl.694

Abstract: 694Background: The impact of primary tumour sidedness has recently been demonstrated in patients with metastatic colorectal cancer (mCRC). Differences in right (R) versus left (L) sided mCRC may be due to differences in consensus molecular… read more here.

Keywords: sidedness; tumour sidedness; crlm; impact primary ... See more keywords

Tumor genomics and sidedness to predict outcomes in metastatic colorectal cancer (mCRC).

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recommendations! Published in 2024 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2024.42.3_suppl.207

Abstract: 207 Background: Tumor sidedness is a prognostic factor and predictive parameter for EGFR monoclonal antibody (mAb) treatment in mCRC. Sidedness is believed to be a surrogate for genomic differences. This study aimed to evaluate genomics… read more here.

Keywords: genomics sidedness; tumor genomics; sidedness; mcrc ... See more keywords