A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.
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DOI: 10.1016/j.ejmech.2021.113436
Abstract: Serious infections caused by multidrug-resistant (MDR) organisms (Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii) present a critical need for innovative drug development. Herein, we describe the preclinical evaluation of YU253911, 2, a novel γ-lactam siderophore antibiotic… read more here.
Keywords: lactam siderophore; pseudomonas aeruginosa; siderophore antibiotic; acinetobacter spp ... See more keywords