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Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkz123
Abstract: Abstract Background Cefiderocol, a novel siderophore cephalosporin, has shown potent activity against Gram-negative bacteria, including MDR pathogens. Cefiderocol is under clinical investigation for the treatment of serious Gram-negative infections including nosocomial pneumonia. Objectives This study…
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Keywords:
healthy adult;
novel siderophore;
siderophore cephalosporin;
cefiderocol novel ... See more keywords
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Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01437-20
Abstract: Cefiderocol is a novel siderophore cephalosporin with antibacterial activity against Gram-negative bacteria, including carbapenem-resistant strains. The standard dosing regimen of cefiderocol is 2 g administered every 8 hours over 3 hours infusion in patients with creatinine clearance (CrCL)…
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Keywords:
sepsis;
population;
infection;
crcl ... See more keywords