Trojan Horse Siderophore Conjugates Induce Pseudomonas aeruginosa Suicide and Qualify the TonB Protein as a Novel Antibiotic Target.
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DOI: 10.1021/acs.jmedchem.2c01489
Abstract: Rising infection rates with multidrug-resistant pathogens calls for antibiotics with novel modes of action. Herein, we identify the inner membrane protein TonB, a motor of active uptake in Gram-negative bacteria, as a novel target in… read more here.
Keywords: trojan horse; suicide; pseudomonas aeruginosa; siderophore conjugates ... See more keywords