Children's anxiety symptoms and salivary immunoglobulin A: A mutual regulatory system?
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Psychobiology"
DOI: 10.1002/dev.21590
Abstract: Anxiety can impact the immune system resulting in negative health outcomes. Salivary immunoglobulin A (sIgA) is a first line of defense against foreign antigens, with lowered levels indicative of weakened mucosal immunity. Little is known… read more here.
Keywords: anxiety symptoms; system; anxiety; salivary immunoglobulin ... See more keywords
Increasing of SIgA serum levels may reflect subclinical intestinal involvement in non-radiographic axial and peripheral spondyloarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05369-w
Abstract: The evidence shows that previous infection with enteric pathogens is a requirement to develop pSpA. Based on our previous results, variances on regulation of SIgA might influence SpA activity; thus, the aim of this study… read more here.
Keywords: spa patients; enteric bacteria; intestinal involvement; subclinical intestinal ... See more keywords
Potential immunological effects of fermentable fibres in athletes
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665120006229
Abstract: Abstract Recent findings point at novel benefits of specific fibres, like inulin, as their fermentation metabolites can improve mucosal immunity and protect against infections (1,2). This outcome is desirable for athletes, who are at increased… read more here.
Keywords: inulin supplementation; immunological effects; supplementation; potential immunological ... See more keywords
Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets
Sign Up to like & getrecommendations! Published in 2020 at "Mucosal Immunology"
DOI: 10.1038/s41385-020-00345-8
Abstract: Mucosal surfaces are colonized by highly diverse commensal microbiota. Coating with secretory IgA (SIgA) promotes the survival of commensal bacteria while it inhibits the invasion by pathogens. Bacterial coating could be mediated by antigen-specific SIgA… read more here.
Keywords: protection; coli o55; secretory iga; germ free ... See more keywords
Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin
Sign Up to like & getrecommendations! Published in 2020 at "Cell Research"
DOI: 10.1038/s41422-020-0336-3
Abstract: Secretory Immunoglobulin A (SIgA) is the most abundant antibody at the mucosal surface. It possesses two additional subunits besides IgA: the joining chain (J-chain) and secretory component (SC). SC is the ectodomain of the polymeric… read more here.
Keywords: chain; secretory immunoglobulin; structural insights; pneumococcal adhesin ... See more keywords
Secret(ory) revealed: the long-awaited structures of secretory IgA
Sign Up to like & getrecommendations! Published in 2020 at "Cell Research"
DOI: 10.1038/s41422-020-0351-4
Abstract: Secretory IgA (SIgA) is a specialized form of antibody present at high concentrations in mucosal secretions, where it acts as the first line of defense of the immune system. In a recent paper published in… read more here.
Keywords: chain; iga; piga; form ... See more keywords
How to assess the effectiveness of nasal influenza vaccines? Role and measurement of sIgA in mucosal secretions
Sign Up to like & getrecommendations! Published in 2019 at "Influenza and Other Respiratory Viruses"
DOI: 10.1111/irv.12664
Abstract: Secretory IgAs (sIgA) constitute the principal isotype of antibodies present in nasal and mucosal secretions. They are secreted by plasma cells adjacent to the mucosal epithelial cells, the site where infection occurs, and are the… read more here.
Keywords: mucosal secretions; measurement siga; mucosal; role ... See more keywords
Transcytosis of IgA Attenuates Salmonella Invasion in Human Enteroids and Intestinal Organoids
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00041-22
Abstract: Secretory IgA (SIgA) is the most abundant antibody type in intestinal secretions where it contributes to safeguarding the epithelium from invasive pathogens like the Gram-negative bacterium, Salmonella enterica serovar Typhimurium (STm). For example, we recently… read more here.
Keywords: iga; sal4; siga; human enteroids ... See more keywords
Secretory Cells are the Primary Source of pIgR in Small Airways.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2021-0548oc
Abstract: Loss of secretory immunoglobulin A (SIgA) is common in COPD small airways and likely contributes to disease progression. We hypothesized loss of SIgA results from reduced expression of pIgR, a chaperone protein needed for SIgA… read more here.
Keywords: cell; small airways; pigr; loss ... See more keywords
Prophylactic Activity of Orally Administered FliD-Reactive Monoclonal SIgA Against Campylobacter Infection
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01011
Abstract: Campylobacter infection is one of the most common causes of bacterial gastroenteritis worldwide and a major global health threat due to the rapid development of antibiotic resistance. Currently, there are no vaccines approved to prevent… read more here.
Keywords: prophylactic activity; infection; flid reactive; campylobacter ... See more keywords
Impact of Biometric Patient Data, Probiotic Supplementation, and Selected Gut Microorganisms on Calprotectin, Zonulin, and sIgA Concentrations in the Stool of Adults Aged 18–74 Years
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12121781
Abstract: Alterations to the intestinal barrier may be involved in the pathogenesis of various chronic diseases. The diagnosis of mucosal barrier disruption has become a new therapeutic target for disease prevention. The aim of this study… read more here.
Keywords: supplementation; impact biometric; siga; zonulin siga ... See more keywords