Resilience to oxidative and nitrosative stress is mediated by the stressosome, RsbP and SigB in Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.201900076
Abstract: A bacterium's ability to thrive in the presence of multiple environmental stressors simultaneously determines its resilience. We showed that activation of the SigBâcontrolled general stress response by mild environmental or energy stress provided significant crossâprotection… read more here.
Keywords: nitrosative stress; stressosome rsbp; sigb; stress ... See more keywords
Rhodomyrtone decreases Staphylococcus aureus SigB activity during exponentially growing phase and inhibits haemolytic activity within membrane vesicles.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.12.019
Abstract: Sigma factor B (SigB) controls the expression of Staphylococcus aureus genes including virulence factors and plays a role in the bacterial secretion system through membrane vesicle production. Inhibition of SigB could attenuate SigB dependent virulence… read more here.
Keywords: membrane vesicles; rhodomyrtone; sigb; sigb activity ... See more keywords
The Virulence and Infectivity of Listeria monocytogenes Are Not Substantially Altered by Elevated SigB Activity
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Immunity"
DOI: 10.1128/iai.00571-22
Abstract: Listeria monocytogenes is a bacterial pathogen capable of causing severe infections but also thriving outside the host. To respond to different stress conditions, L. monocytogenes mainly utilizes the general stress response regulon, which largely is… read more here.
Keywords: stress; sigb activity; infectivity; listeria monocytogenes ... See more keywords
Listeria monocytogenes Requires the RsbX Protein To Prevent SigB Activation under Nonstressed Conditions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bacteriology"
DOI: 10.1128/jb.00486-21
Abstract: Pathogenic bacteria need to sense and respond to stresses to survive harsh environments and also be able to turn off the response when no longer facing stress. Activity of the stress sigma factor SigB in… read more here.
Keywords: sigb activation; listeria monocytogenes; sigb; stress ... See more keywords
Staphylococcus aureus Regulator Sigma B is Important to Develop Chronic Infections in Hematogenous Murine Osteomyelitis Model
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DOI: 10.3390/pathogens6030031
Abstract: Staphylococcus aureus is a major pathogen causing bone infections that can become chronic and difficult to treat. Recently, we described the mechanism employed by S. aureus to switch to small colony variants (SCVs) and trigger… read more here.
Keywords: staphylococcus aureus; osteomyelitis model; bone; sigb ... See more keywords