Pleiotropic anti-anti-sigma factor BldG is phosphorylated by several anti-sigma factor kinases in the process of activating multiple sigma factors in Streptomyces coelicolor A3(2).
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144883
Abstract: The anti-anti-sigma factor BldG has a pleiotropic function in Streptomyces coelicolor A3(2), regulating both morphological and physiological differentiation. Together with the anti-sigma factor UshX, it participates in a partner-switching activation of the sigma factor σH,… read more here.
Keywords: sigma; bldg; sigma factor; sigma factors ... See more keywords
Alternative Sigma Factor of Staphylococcus aureus Interacts with the Cognate Antisigma Factor Primarily Using Its Domain 3.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00881
Abstract: σB, an alternative sigma factor, is usually employed to tackle the general stress response in Staphylococcus aureus and other Gram-positive bacteria. This protein, involved in S. aureus-mediated pathogenesis, is typically blocked by RsbW, an antisigma… read more here.
Keywords: alternative sigma; staphylococcus aureus; factor; sigma factor ... See more keywords
Expression of Heterologous Sigma Factor Expands the Searchable Space for Biofuel Tolerance Mechanisms.
Sign Up to like & getrecommendations! Published in 2017 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.6b00375
Abstract: Microorganisms can produce hydrocarbons that can serve as replacements or additions to conventional liquid fuels for use in the transportation sector. However, a common problem in the microbial synthesis of biofuels is that these compounds… read more here.
Keywords: tolerance; sigma; heterologous sigma; expression ... See more keywords
Sigma Factor-Mediated Tuning of Bacterial Cell-Free Synthetic Genetic Oscillators
Sign Up to like & getrecommendations! Published in 2018 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.8b00300
Abstract: Cell-free transcription–translation provides a simplified prototyping environment to rapidly design and study synthetic networks. Despite the presence of a well characterized toolbox of genetic elements, examples of genetic networks that exhibit complex temporal behavior are… read more here.
Keywords: mediated tuning; cell; tuning bacterial; cell free ... See more keywords
Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12667-y
Abstract: Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that infects immunocompromised and cystic fibrosis patients. Treatment is difficult due to antibiotic resistance, and new antimicrobials are needed to treat infections. The alternative sigma factor 54 (σ54,… read more here.
Keywords: alternative sigma; factor rpon; pseudomonas aeruginosa; virulence ... See more keywords
Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41183-4
Abstract: AbstractσE is one of the 13 sigma factors encoded by the Mycobacterium tuberculosis chromosome, and its involvement in stress response and virulence has been extensively characterized. Several sigma factors are post-translationally regulated by proteins named… read more here.
Keywords: rsea; sigma; tuberculosis; factor ... See more keywords
Technical Details of the Sigma Factor Alarm Method within Alpha CAMs.
Sign Up to like & getrecommendations! Published in 2020 at "Health Physics"
DOI: 10.1097/hp.0000000000001341
Abstract: ABSTRACT Some test must be applied to the low-level count data from alpha continuous air monitors (CAMs) to determine if the count is statistically significant (i.e., significantly above background). The method should be as sensitive… read more here.
Keywords: details sigma; alpha cams; sigma factor; alarm ... See more keywords
Control of solvent production by sigma‐54 factor and the transcriptional activator AdhR in Clostridium beijerinckii
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13505
Abstract: Clostridia are obligate anaerobic bacteria that can produce solvents such as acetone, butanol and ethanol. Alcohol dehydrogenases (ADHs) play a key role in solvent production; however, their regulatory mechanisms remain largely unknown. In this study,… read more here.
Keywords: production; solvent production; beijerinckii; transcriptional activator ... See more keywords
Activation of the Listeria monocytogenes Stressosome in the Intracellular Eukaryotic Environment
Sign Up to like & getrecommendations! Published in 2021 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00397-21
Abstract: The response to stress mediated by the alternative sigma factor SigB has been extensively characterized in Bacillus subtilis and Listeria monocytogenes. These bacteria sense stress using a supramacromolecular complex, the stressosome, which triggers a cascade… read more here.
Keywords: stressosome; stress; sigma factor; listeria monocytogenes ... See more keywords
An Extracytoplasmic Function Sigma/Anti-Sigma Factor System Regulates β-Glucanase Expression in Tannerella forsythia in Response to Fusobacterium nucleatum Sensing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00313-22
Abstract: Previous studies have shown that F. nucleatum forms robust biofilms with T. forsythia utilizing glucose from the hydrolysis of β-glucans by T. forsythia β-glucanase, induced by F. nucleatum. In this study, we showed that a… read more here.
Keywords: sigma factor; glucanase; anti sigma; nucleatum ... See more keywords
Regulatory Role of Anti-Sigma Factor RsbW in Clostridioides difficile Stress Response, Persistence, and Infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00466-22
Abstract: Pathogens like Clostridioides difficile face a range of stresses in the environment and within the host. Alternative transcriptional factors like sigma factor B (σB) enable the bacterium to respond quickly to different stresses. ABSTRACT The… read more here.
Keywords: stress; sigma factor; clostridioides difficile; rsbw ... See more keywords