Drug-like Inhibitors of DC-SIGN Based on a Quinolone Scaffold.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00067
Abstract: DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) is a pattern recognition receptor expressed on immune cells and involved in the recognition of carbohydrate signatures present on various pathogens, including HIV, Ebola, and SARS-CoV-2. Therefore, developing… read more here.
Keywords: inhibitors sign; drug like; quinolone scaffold; sign based ... See more keywords
Finite-sample generalized confidence distributions and sign-based robust estimators in median regressions with heterogeneous dependent errors
Sign Up to like & getrecommendations! Published in 2020 at "Econometric Reviews"
DOI: 10.1080/07474938.2020.1772568
Abstract: Abstract We study the problem of estimating the parameters of a linear median regression without any assumption on the shape of the error distribution – including no condition on the existence of moments – allowing… read more here.
Keywords: confidence; sample generalized; confidence distributions; finite sample ... See more keywords
Spatial-Sign Based Maxsum Test for High Dimensional Location Parameters
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DOI: 10.5705/ss.202024.0051
Abstract: In this study, we explore a robust testing procedure for the high-dimensional location parameters testing problem. Initially, we introduce a spatial-sign based max-type test statistic, which exhibits excellent performance for sparse alternatives. Subsequently, we demonstrate… read more here.
Keywords: high dimensional; test; dimensional location; sign based ... See more keywords