Dendrimer‐Based Signal Amplification of Click‐Labelled DNA in Situ
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700209
Abstract: The in vivo incorporation of alkyne‐modified bases into the genome of cells is today the basis for the efficient detection of cell proliferation. Cells are grown in the presence of ethinyl‐dU (EdU), fixed and permeabilised.… read more here.
Keywords: click labelled; dendrimer based; labelled dna; signal amplification ... See more keywords
Ultrasensitive Electrochemiluminescence Biosensor for mRNA Based on Polymerase Assisted Signal Amplification
Sign Up to like & getrecommendations! Published in 2017 at "Electroanalysis"
DOI: 10.1002/elan.201600590
Abstract: A novel biosensor for ultra-trace mRNA sensing was constructed based on isothermal circular strand-replacement polymerization (CSRP) to amplify the electrochmeiluminescence (ECL) signal by combining quantum dots (CdTe) as luminophore. After the hairpin-like capture DNA was… read more here.
Keywords: biosensor; ultrasensitive electrochemiluminescence; target; target mrna ... See more keywords
A strand displacement signal amplification-assisted fluorescence assay for sensitive detection of microRNA.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of separation science"
DOI: 10.1002/jssc.202300123
Abstract: MicroRNA is a vital biomarker because of its abnormal expression in the emergence and development of diseases, especially in cancers. Herein, a label-free fluorescent sensing platform is proposed for detecting microRNA-21, coupled with the cascade… read more here.
Keywords: signal amplification; amplification assisted; displacement signal; detection ... See more keywords
DNA Logic Circuits for Cancer Theranostics.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202108008
Abstract: Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment (TME) and biomarkers has been an emerging approach for precision medicine. DNA nanotechnology dynamically controls the self-assembly of DNA molecules at the nanometer scale to… read more here.
Keywords: signal amplification; dna logic; logic circuits; cancer ... See more keywords
An Artificial Miniaturized Peroxidase for Signal Amplification in Lateral Flow Immunoassays.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207949
Abstract: Signal amplification strategies are widely used for improving the sensitivity of lateral flow immunoassays (LFiAs). Herein, the artificial miniaturized peroxidase Fe(III)-MimochromeVI*a (FeMC6*a), immobilized on gold nanoparticles (AuNPs), is used as a strategy to obtain catalytic… read more here.
Keywords: peroxidase; signal amplification; artificial miniaturized; lateral flow ... See more keywords
Hierarchical Porous Metal-Organic Framework as Biocatalytic Microreactor for Enzymatic Biofuel Cell-Based Self-Powered Biosensing of MicroRNA Integrated with Cascade Signal Amplification.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202301654
Abstract: Enzymatic biofuel cells have become powerful tools in biosensing, which however generally suffer from the limited loading efficiency as well as low catalytic activity and poor stability of bioenzymes. Herein, the hierarchical porous metal-organic frameworks… read more here.
Keywords: hierarchical porous; signal amplification; enzymatic biofuel; metal organic ... See more keywords
Ionic Signal Amplification of DNA in a Nanopore
Sign Up to like & getrecommendations! Published in 2022 at "Small Methods"
DOI: 10.1002/smtd.202200761
Abstract: Ionic signal amplification is a key challenge for single‐molecule analyses by solid‐state nanopore sensing. Here, a permittivity gradient approach for amplifying ionic blockade characteristics of DNA in a nanofluidic channel is reported. The transmembrane ionic… read more here.
Keywords: ionic current; ionic signal; dna; signal amplification ... See more keywords
Nucleic acid-based electrochemical biosensor: Recent advances in probe immobilization and signal amplification strategies.
Sign Up to like & getrecommendations! Published in 2021 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1765
Abstract: With the increasing importance of accurate and early disease diagnosis and the development of personalized medicine, DNA-based electrochemical biosensor has attracted broad scientific and clinical interests in the past decades due to its unique hybridization… read more here.
Keywords: electrochemical biosensor; probe immobilization; recent advances; based electrochemical ... See more keywords
Antigen Retrieval and Signal Amplification.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1948-3_5
Abstract: Immunohistochemistry (IHC) offers a valuable method for determining the spatial distribution of proteins in cells and tissues. Fixation of tissues prior IHC enables their long-term stability and preserves tissue morphology; however, downstream analysis of protein… read more here.
Keywords: amplification; signal amplification; retrieval signal; antigen retrieval ... See more keywords
Indirect competitive-structured electrochemical immunosensor for tetrabromobisphenol A sensing using CTAB-MnO2 nanosheet hybrid as a label for signal amplification
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03368-7
Abstract: Tetrabromobisphenol A (TBBPA) is a kind of brominated flame retardant that is usually added to products to reduce their flame retardancy. However, its extensive use has resulted in their residues being found in the environment,… read more here.
Keywords: mno2 nanosheet; indirect competitive; immunosensor; tetrabromobisphenol ... See more keywords
Cascaded DNA circuits-programmed self-assembly of spherical nucleic acids for high signal amplification
Sign Up to like & getrecommendations! Published in 2019 at "Science China Chemistry"
DOI: 10.1007/s11426-019-9603-3
Abstract: Signal amplification is an important issue in DNA nanotechnology and molecular diagnostics. In this work, we report a strategy for the catalytic self-assembly of spherical nucleic acids (SNAs) programmed by two-layer cascaded DNA circuits through… read more here.
Keywords: spherical nucleic; self assembly; dna; assembly spherical ... See more keywords