A novel GSTe2 involved in metamorphosis by regulating 20E signal pathway in Tribolium castaneum.
Sign Up to like & getrecommendations! Published in 2023 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21989
Abstract: Insect-specific epsilon glutathion S-transferases (GSTs) are a class of multifunctional GST superfamily, which play important roles in detoxification of xenobiotic substances. Most research on GSTs has focused on insecticide detoxification and resistance, with little research… read more here.
Keywords: metamorphosis; signal pathway; castaneum; 20e signal ... See more keywords
Activated hippo signal pathway inhibits cell proliferation and promotes apoptosis in NK/T cell lymphoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2174
Abstract: Natural Killer T–Cell Lymphoma (NKTCL) is a subtype of Non‐Hodgkin's Lymphoma, and its morbidity is ranked the first of T‐Cell Lymphoma. Hippo signaling pathway is involved in the pathogenesis of tumors. However, the role of… read more here.
Keywords: hippo signal; activated hippo; signal pathway; cell ... See more keywords
Carbon Monoxide-Releasing Molecule-3 Alleviates Kupffer Cell Pyroptosis Induced by Hemorrhagic Shock and Resuscitation via sGC-cGMP Signal Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation"
DOI: 10.1007/s10753-021-01419-w
Abstract: Following hepatic ischemia-reperfusion injury, Kupffer cells could be activated by inflammatory factors released from damaged hepatocytes. Carbon monoxide (CO)-releasing molecule (CORM)-3, a water-soluble transition metal carbonyl, exhibits excellent anti-inflammatory and anti-pyroptosis properties. We investigated whether… read more here.
Keywords: pyroptosis kupffer; pyroptosis; kupffer cells; resuscitation ... See more keywords
Banxia Xiexin Decoction (半夏泻心汤) Treats Diabetic Gastroparesis through PLC-IP3-Ca2+/NO-cGMP-PKG Signal Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-3077-8
Abstract: To test the effect of Banxia Xiexin Decoction (半夏泻心汤, BXD) on the contraction and relaxation of gastric smooth muscle (SM) in diabetic gastroparesis (DGP) model rats, and to explore the mechanism of BXD in the… read more here.
Keywords: bxd; cgmp pkg; plc ip3; group ... See more keywords
Mercuric Chloride Induced Ovarian Oxidative Stress by Suppressing Nrf2-Keap1 Signal Pathway and its Downstream Genes in Laying Hens
Sign Up to like & getrecommendations! Published in 2018 at "Biological Trace Element Research"
DOI: 10.1007/s12011-018-1244-y
Abstract: The present study evaluated the effects of mercury chloride (HgCl2) on follicular atresia rate, sex hormone secretion, and ovarian oxidative stress in laying hens. Antioxidant enzyme genes and the nuclear factor erythroid 2-related factor 2… read more here.
Keywords: ovarian oxidative; laying hens; keap1 signal; nrf2 keap1 ... See more keywords
HMGB1 was negatively regulated by HSF1 and mediated the TLR4/MyD88/NF-κB signal pathway in asthma.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.117120
Abstract: AIMS The present study explored the function and regulatory mechanism of High mobility group box 1 (HMGB1) in asthma. MAIN METHODS OVA (ovalbumin)-induced asthmatic mice model and LPS-treated cellular model were established in this study.… read more here.
Keywords: hmgb1; negatively regulated; signal pathway; regulated hsf1 ... See more keywords
Synthetic biology applications of the yeast mating signal pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2021.09.007
Abstract: Cell fusion is a fundamental biological process that is involved in the development of most eukaryotic organisms. During the fusion process in Saccharomyces cerevisiae, cells respond to pheromones to trigger the MAPK (mitogen-activated protein kinase)… read more here.
Keywords: mating signal; pathway; biology; signal pathway ... See more keywords
The multidrug resistance can be reversed for the decrease of P-gp and LRP by inhibiting PI3K/Akt/NF-κB signal pathway in nasopharynx carcinoma
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DOI: 10.1042/bsr20190239
Abstract: Abstract Aim: To investigate the relationship between PI3K/Akt/NF-κB cellular signal pathway and the expression of P-gp and LRP in multidrug resistance (MDR) cell of nasopharyngeal carcinoma. Method: The PI3K, p-Akt and NF-κB/p65 as the activity… read more here.
Keywords: akt signal; carcinoma; signal pathway; pi3k akt ... See more keywords
Relationship between uterine smooth muscular CPI-17-signal pathway-mediated Ca2+ sensitivity changes and uterine atony-induced postpartum haemorrhage
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2018.1504206
Abstract: Abstract This study aimed to investigate the changes of protein kinase C (PKC)-potentiated phosphatase inhibitor of 17 ku (CPI-17) expression, PKC activity and Rho kinase activity in the maternal uterine smooth muscle (USM), and their… read more here.
Keywords: ca2 sensitivity; uai pph; cpi; cpi signal ... See more keywords
Autophagy plays a role in the prolongation of the lifespan of Caenorhabditis elegans by astaxanthin.
Sign Up to like & getrecommendations! Published in 2020 at "Rejuvenation research"
DOI: 10.1089/rej.2020.2355
Abstract: Astaxanthin, a xanthophyll belonging to the family of carotenoids, is a potent antioxidant. The effect of astaxanthin on longevity and its physiological and molecular mechanism are still unclear. In this study, we proved that astaxanthin… read more here.
Keywords: role prolongation; caenorhabditis elegans; lifespan caenorhabditis; signal pathway ... See more keywords
Shikonin inhibits growth, invasion and glycolysis of nasopharyngeal carcinoma cells through inactivating the phosphatidylinositol 3 kinase/AKT signal pathway
Sign Up to like & getrecommendations! Published in 2020 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000920
Abstract: Nasopharyngeal carcinoma (NPC) is a malignant tumor which is commonly found in East Asia and Africa. The present clinical treatment of NPC is still mainly based on chemotherapeutics and is prone to drug resistance and… read more here.
Keywords: akt signal; treatment; invasion; signal pathway ... See more keywords