Social defeat stress induces phosphorylation of extracellular signal‐regulated kinase in the leptomeninges in mice
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12051
Abstract: Animal studies using various stress models have shown that excessive environmental stress induces depression? and anxiety?like behaviors through inflammatory responses in the brain and periphery. Although the leptomeningeal cells have multiple functions related to inflammatory… read more here.
Keywords: extracellular signal; stress induces; regulated kinase; stress ... See more keywords
Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.01.019
Abstract: Egr-1, an immediate-early gene product and master regulator was originally described as a phosphoprotein following its discovery in the 1980s. However specific residue(s) phosphorylated in Egr-1 remain elusive. Here we phosphorylated recombinant Egr-1 in vitro with… read more here.
Keywords: extracellular signal; ps26 mab; egr; kda species ... See more keywords
The pivotal role of extracellular signal-regulated kinase in gap junction-mediated regulation of TXNIP.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2017.07.001
Abstract: Gap junctions (GJs) play a major role in the control of cell structure, function, and metabolism. However, the molecular mechanisms involved are still poorly understood. Given that thioredoxin-interacting protein (TXNIP) regulates a broad range of… read more here.
Keywords: kinase; erk; extracellular signal; regulated kinase ... See more keywords
Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility
Sign Up to like & getrecommendations! Published in 2018 at "iScience"
DOI: 10.1016/j.isci.2018.11.025
Abstract: Summary Extracellular signal-regulated kinase (ERK) plays critical roles in T cell development in the thymus. Nevertheless, the dynamics of ERK activity and the role of ERK in regulating thymocyte motility remain largely unknown due to… read more here.
Keywords: extracellular signal; signal regulated; motility; cell ... See more keywords
Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.12.003
Abstract: Maduramicin, a polyether ionophore antibiotic used as an anticoccidial agent in poultry industry, has been reported to be toxic to animals and humans if improperly used or by accident, resulting in heart failure, skeletal muscle… read more here.
Keywords: h9c2 cells; extracellular signal; activated protein; cytotoxicity ... See more keywords
Chemical signal regulated injectable coacervate hydrogels
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc06935k
Abstract: In the quest for stimuli-responsive materials with specific, controllable functions, coacervate hydrogels have become a promising candidate, featuring sensitive responsiveness to environmental signals enabling control over sol–gel transitions. However, conventional coacervation-based materials are regulated by… read more here.
Keywords: chemical signal; regulated injectable; signal regulated; coacervate hydrogels ... See more keywords
In Vitro Anti-Inflammatory Activity of Ilex cornuta Extract Mediated by Inhibition of Extracellular Signal-Regulated Kinase Phosphorylation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal food"
DOI: 10.1089/jmf.2016.3913
Abstract: Ilex cornuta, commonly known as Chinese holly, is an evergreen shrub from the family Aquifoliaceae, and it is widely distributed in Korea and China. In folk medicine, the leaves of I. cornuta are used for… read more here.
Keywords: anti inflammatory; ilex cornuta; extracellular signal; mediated inhibition ... See more keywords
Gallotannin Improves the Photoaged-Related Proteins by Extracellular Signal-Regulated Kinases/c-Jun N-Terminal Kinases Signaling Pathway in Human Epidermal Keratinocyte Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal food"
DOI: 10.1089/jmf.2017.4096
Abstract: Tannins are a type of polyphenols found in several fruits such as grapes and berries, and nuts such as aronias and acorns. Both hydrolyzable tannins and condensed tannins are referred to as tannins. Among the… read more here.
Keywords: kinases jun; jun terminal; extracellular signal; regulated kinases ... See more keywords
WNT1-inducible signalling pathway protein 1 stabilizes atherosclerotic plaques in apolipoprotein-E-deficient mice via the focal adhesion kinase/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003195
Abstract: Background: The migration, proliferation and apoptosis of vascular smooth muscle cells (VSMCs) are critical for plaque stability. WNT-inducible signalling pathway protein-1 (WISP1), a member of the CCN family of extracellular matrix proteins, can expedite the… read more here.
Keywords: kinase; extracellular signal; pathway; signal regulated ... See more keywords
Ageing causes an aortic contractile dysfunction phenotype by targeting the expression of members of the extracellular signal‐regulated kinase pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17118
Abstract: The extracellular signal‐regulated kinase (ERK) pathway is a well‐known regulator of vascular smooth muscle cell proliferation, but it also serves as a regulator of caldesmon, which negatively regulates vascular contractility. This study examined whether aortic… read more here.
Keywords: erk phosphorylation; aortic contractile; extracellular signal; expression ... See more keywords
Live imaging of extracellular signal‐regulated kinase and protein kinase A activities during thrombus formation in mice expressing biosensors based on Förster resonance energy transfer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13723
Abstract: Essentials Spatiotemporal regulation of protein kinases during thrombus formation remains elusive in vivo. Activities of protein kinases were live imaged in mouse platelets at laser‐ablated arterioles. Protein kinase A was activated in the dislodging platelets… read more here.
Keywords: kinase; thrombus formation; extracellular signal; regulated kinase ... See more keywords