Signal-transducing adaptor protein-1 and -2 in hematopoiesis and diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental hematology"
DOI: 10.1016/j.exphem.2021.11.002
Abstract: Inflammatory and immune signals are involved in stressed hematopoiesis under myeloablation, infection, chronic inflammation, and aging. These signals also affect malignant pathogenesis, and the dysregulated immune environment which causes the resistance to treatment. Upon activation,… read more here.
Keywords: protein; hematopoiesis; adaptor protein; transducing adaptor ... See more keywords
Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-43535-6
Abstract: Variants of triggering receptor expressed on myeloid cells 2 (TREM2) are associated with an increased incidence of Alzheimer’s disease, as well as other neurodegenerative disorders. Using a newly developed, highly sensitive reporter cell model, consisting… read more here.
Keywords: transducing trem2; apoptotic cells; ligands apoptotic; aminophospholipids signal ... See more keywords