Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Cell"
DOI: 10.1016/j.devcel.2020.01.004
Abstract: Summary To divide in a tissue, both normal and cancer cells become spherical and mechanically stiffen as they enter mitosis. We investigated the effect of oncogene activation on this process in normal epithelial cells. We… read more here.
Keywords: mechanics; confinement; oncogenic signaling; signaling alters ... See more keywords
BMP signaling alters aquaporin-4 expression in the mouse cerebral cortex
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89997-5
Abstract: Aquaporin-4 (AQP4) is a predominant water channel expressed in astrocytes in the mammalian brain. AQP4 is crucial for the regulation of homeostatic water movement across the blood–brain barrier (BBB). Although the molecular mechanisms regulating AQP4… read more here.
Keywords: bmp signaling; cerebral cortex; aqp4; mouse cerebral ... See more keywords