Fusion with Promiscuous Gα16 Subunit Reveals Signaling Bias at Muscarinic Receptors
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DOI: 10.3390/ijms221810089
Abstract: A complex evaluation of agonist bias at G-protein coupled receptors at the level of G-protein classes and isoforms including non-preferential ones is essential for advanced agonist screening and drug development. Molecular crosstalk in downstream signaling… read more here.
Keywords: muscarinic receptors; agonist bias; signaling bias; bias ... See more keywords