Integration of hypoxic HIF-α signaling in blood cancers
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DOI: 10.1038/onc.2017.119
Abstract: Hypoxia (low O2) is a fundamental microenvironmental determinant of bone marrow (BM) pathophysiology. Recent data from molecular and clinical studies indicate that hematopoiesis and leukemogenesis are dependent upon hypoxia-inducible factors (HIFs), a family of essential… read more here.
Keywords: hif signaling; integration hypoxic; hypoxic hif; blood ... See more keywords
Cell–cell signaling in blood vessel development and function
Sign Up to like & getrecommendations! Published in 2018 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.201708610
Abstract: The blood vasculature is an organ pervading all other organs (almost). During vascular development, cell–cell signaling by extracellular ligands and cell surface receptors ensure that new vessels sprout into non‐vascularized regions and simultaneously acquire organ‐specific… read more here.
Keywords: cell; cell signaling; blood; cell cell ... See more keywords