Localization of interleukin-6 signaling complex in epithelialized apical lesions of endodontic origin.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical oral investigations"
DOI: 10.1007/s00784-020-03738-y
Abstract: OBJECTIVES We aimed to determine the immunolocalization patterns of the interleukin (IL)-6 signaling complex in epithelialized and non-epithelialized apical lesions of endodontic origin (ALEOs). MATERIALS AND METHODS Epithelialized (n = 8) and non-epithelialized (n = 7) ALEOs were obtained… read more here.
Keywords: signaling complex; apical lesions; epithelialized apical; interleukin signaling ... See more keywords
Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.05.056
Abstract: SUMMARY Throughout the CNS, interactions between pre- and postsynaptic adhesion molecules establish normal synaptic structure and function. Leucine-rich repeat (LRR) domain-containing proteins are a large family that has a diversity of ligands, and their absence… read more here.
Keywords: postsynaptic glutamate; signaling complex; expression lrit3; expression ... See more keywords
The STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008819
Abstract: The striatin-interacting phosphatase and kinase (STRIPAK) multi-subunit signaling complex is highly conserved within eukaryotes. In fungi, STRIPAK controls multicellular development, morphogenesis, pathogenicity, and cell-cell recognition, while in humans, certain diseases are related to this signaling… read more here.
Keywords: signaling complex; gul1; shuttles endosomes; phosphorylation ... See more keywords
Structural insights into the assembly and activation of the IL‐27 signaling complex
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DOI: 10.15252/embr.202255450
Abstract: Interleukin 27 (IL‐27) is a heterodimeric cytokine that elicits potent immunosuppressive responses. Comprised of EBI3 and p28 subunits, IL‐27 binds GP130 and IL‐27Rα receptor chains to activate the JAK/STAT signaling cascade. However, how these receptors… read more here.
Keywords: cytokine; structural insights; assembly activation; signaling complex ... See more keywords