Preprint Highlight: Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology of the cell"
DOI: 10.1091/mbc.p22-10-1005
Abstract: Standard genomic and proteomic profiling methods for colorectal tumors do not always translate into reliable precision medicine outcomes. Tumor plasticity mechanisms can result in nongenetic responses to targeted therapies, calling for a functional approach using… read more here.
Keywords: spatial proteomics; preprint; colorectal cancer; signaling crosstalk ... See more keywords
Opioids and Vitamin C: Known Interactions and Potential for Redox-Signaling Crosstalk
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DOI: 10.3390/antiox11071267
Abstract: Opioids are among the most widely used classes of pharmacologically active compounds both clinically and recreationally. Beyond their analgesic efficacy via μ opioid receptor (MOR) agonism, a prominent side effect is central respiratory depression, leading… read more here.
Keywords: redox; mor; opioids vitamin; mor activation ... See more keywords