BAFF signaling in health and disease.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.06.014
Abstract: BAFF is a critical cytokine supporting the survival of mature naïve B cells, acting through the BAFFR receptor. Recent studies show that BAFF and BAFFR are also required for the survival of memory B cells,… read more here.
Keywords: signaling health; baff signaling; baffr; health disease ... See more keywords
Pleiotropic GPCR signaling in health and disease
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.05.013
Abstract: This Special Issue of Molecular and Cellular Endocrinology on ‘Pleiotropic G protein-coupled receptor (GPCR) signaling in health and disease’ illustrates the exquisite complexity of GPCR signal systems, current approaches to decode this complexity and progress… read more here.
Keywords: signaling health; endocrinology; gpcr signaling; health disease ... See more keywords
Lysosome trafficking and signaling in health and neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.05.015
Abstract: Lysosomes, single-membrane organelles defined by a uniquely strong acidic lumenal pH and high content of acid hydrolases, are the shared degradative compartments of the endocytic and autophagic pathways. These pathways, and especially lysosomes, are points… read more here.
Keywords: signaling health; lysosome trafficking; neurodegenerative diseases; health neurodegenerative ... See more keywords
FGF/FGFR signaling in health and disease
Sign Up to like & getrecommendations! Published in 2020 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00222-7
Abstract: Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR) signaling has crucial roles in a multitude of processes during embryonic development and adult homeostasis by regulating cellular lineage commitment, differentiation, proliferation, and apoptosis of… read more here.
Keywords: signaling health; fgf; fgfr signaling; fgf fgfr ... See more keywords
Cannabinoid signaling in health and disease.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2016-0346
Abstract: Cannabis sativa has long been used for medicinal purposes. To improve safety and efficacy, compounds from C. sativa were purified or synthesized and named under an umbrella group as cannabinoids. Currently, several cannabinoids may be… read more here.
Keywords: signaling health; physiology; pharmacology; health disease ... See more keywords
Molecular Physiology of Bile Acid Signaling in Health, Disease and Aging.
Sign Up to like & getrecommendations! Published in 2020 at "Physiological reviews"
DOI: 10.1152/physrev.00049.2019
Abstract: Over the last two decades, bile acids (BAs) have become established as important signaling molecules that enable fine-tuned inter-tissue communication from the liver, their site of production, over the intestine, where they are modified by… read more here.
Keywords: signaling health; physiology bile; acid signaling; physiology ... See more keywords
The role of PD-1 signaling in health and immune-related diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1163633
Abstract: Programmed cell death 1 receptor (PD-1) and its ligands constitute an inhibitory pathway to mediate the mechanism of immune tolerance and provide immune homeostasis. Significantly, the binding partners of PD-1 and its associated ligands are… read more here.
Keywords: role; immune related; related diseases; signaling health ... See more keywords
Cardiac Sarcomere Signaling in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416223
Abstract: The cardiac sarcomere is a triumph of biological evolution wherein myriad contractile and regulatory proteins assemble into a quasi-crystalline lattice to serve as the central point upon which cardiac muscle contraction occurs. This review focuses… read more here.
Keywords: sarcomere signaling; health disease; cardiac sarcomere; signaling health ... See more keywords