SOCE and STIM1 signaling in the heart: Timing and location matter.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.11.008
Abstract: Store operated Ca2+ entry (SOCE) is an ancient and ubiquitous Ca2+ signaling pathway discovered decades ago, but the function of SOCE in human physiology is only now being revealed. The relevance of this pathway to… read more here.
Keywords: stim1; stim1 signaling; soce stim1; signaling heart ... See more keywords
CaMKII signaling in heart diseases: Emerging role in diabetic cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.01.001
Abstract: Calcium/calmodulin-dependent protein kinase II (CaMKII) is upregulated in diabetes and significantly contributes to cardiac remodeling with increased risk of cardiac arrhythmias. Diabetes is frequently associated with atrial fibrillation, coronary artery disease, and heart failure, which… read more here.
Keywords: camkii signaling; diseases emerging; heart diseases; camkii ... See more keywords
Insulin signaling in the heart is directly and early impaired by growth hormone.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-21-0242
Abstract: Growth hormone (GH) exerts major actions in cardiac growth and metabolism. Considering the important role of insulin in the heart and the well-established anti-insulin effects of GH, cardiac insulin resistance may play a role in… read more here.
Keywords: signaling heart; growth hormone; heart; insulin signaling ... See more keywords