Articles with "signaling impact" as a keyword



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Changes in PGC‐1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.00709

Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive impairment that increasingly afflicts the elderly population. Soluble oligomers (AβOs) has been implicated in AD pathogenesis: however, the molecular events underlying a role for Aβ… read more here.

Keywords: changes pgc; sirt1 signaling; pgc sirt1; signaling impact ... See more keywords