Abstract 4955: Kurarinone, a natural notch signaling inhibitor and modulator of breast cancer stemness
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4955
Abstract: Aberrant activation of Notch signaling pathway plays an important role in breast cancer development, progression, and stem cell renewal. Activation of Notch signaling is triggered by the interaction of Notch receptors with different ligands expressed… read more here.
Keywords: breast cancer; notch signaling; notch; signaling inhibitor ... See more keywords
Effects of NOTCH1 signaling inhibitor γ-secretase inhibitor II on growth of cancer stem cells.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2018.9377
Abstract: The present study aimed to observe the effect of the Notch1 signaling inhibitor γ-secretase inhibitor II (GSI II) on the growth and differentiation of tumor cells. The tumor cell line U87 was grown in serum-free… read more here.
Keywords: inhibitor secretase; inhibitor; notch1 signaling; signaling inhibitor ... See more keywords