TGFβ signaling limits lineage plasticity in prostate cancer
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DOI: 10.1371/journal.pgen.1007409
Abstract: Although treatment options for localized prostate cancer (CaP) are initially effective, the five-year survival for metastatic CaP is below 30%. Mutation or deletion of the PTEN tumor suppressor is a frequent event in metastatic CaP,… read more here.
Keywords: signaling limits; limits lineage; prostate cancer; lineage plasticity ... See more keywords