Comparative Photoaffinity Profiling of Omega-3 Signaling Lipid Probes Reveals Prostaglandin Reductase 1 as a Metabolic Hub in Human Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06827
Abstract: The fish oil constituent docosahexaenoic acid (DHA, 22:6 n-3) is a signaling lipid with anti-inflammatory properties. The molecular mechanisms underlying the biological effect of DHA are poorly understood. Here, we report the design, synthesis, and… read more here.
Keywords: omega signaling; human macrophages; comparative photoaffinity; signaling lipid ... See more keywords
Exercise alters the molecular pathways of insulin signaling and lipid handling in maternal tissues of obese pregnant mice
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DOI: 10.14814/phy2.14202
Abstract: Obesity during gestation adversely affects maternal and infant health both during pregnancy and for long afterwards. However, recent work suggests that a period of maternal exercise during pregnancy can improve metabolic health of the obese… read more here.
Keywords: pregnancy; signaling lipid; obese pregnant; exercise ... See more keywords