Thyroid Hormone Signaling and the Liver
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31296
Abstract: Thyroid hormone (TH) plays a critical role in maintaining metabolic homeostasis throughout life. It is well known that the liver and thyroid are intimately linked, with TH playing important roles in de novo lipogenesis, beta‐oxidation… read more here.
Keywords: hormone; hormone signaling; signaling liver; liver thyroid ... See more keywords
Notch Signaling and Liver Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-55031-8_6
Abstract: Interactions between liver cells are closely regulated by Notch signaling. Notch signaling has been reported clinically related to bile duct hypogenesis in Alagille syndrome, which is caused by mutations in the Jagged1 gene. Notch activation… read more here.
Keywords: signaling liver; hepatitis virus; cancer; notch signaling ... See more keywords
Necroptosis Signaling in Liver Diseases: An Update.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104439
Abstract: The apoptosis alternate cell death pathways are extensively studied in recent years and their significance has been well recognized. With identification of newer cell death pathways, the therapeutic opportunities to modulate cell death have indeed… read more here.
Keywords: necroptosis signaling; necroptosis signalling; liver diseases; necroptosis ... See more keywords
Growth Hormone Signaling in Liver Diseases: Therapeutic Potentials and Controversies
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in Liver Disease"
DOI: 10.1055/a-2015-1359
Abstract: Growth hormone (GH) and downstream insulin-like growth factor 1 (IGF1) signaling mediate growth and metabolism. GH deficiency causes short stature or dwarfism, and excess GH causes acromegaly. Although the association of GH/IGF1 signaling with liver… read more here.
Keywords: liver; igf1 signaling; growth hormone; signaling liver ... See more keywords
Hippo Signaling in the Liver – A Long and Ever-Expanding Story
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2019.00033
Abstract: The first description of Hippo signaling in mammals a little more than 10 years ago showed a striking phenotype in the liver, linking the role of this signaling pathway to organ size control and carcinogenesis.… read more here.
Keywords: hippo; hippo signaling; liver long; signaling liver ... See more keywords
Purinergic Signaling in Liver Pathophysiology
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.718429
Abstract: Extracellular nucleosides and nucleotides activate a group of G protein-coupled receptors (GPCRs) known as purinergic receptors, comprising adenosine and P2Y receptors. Furthermore, purinergic P2X ion channels are activated by ATP. These receptors are expressed in… read more here.
Keywords: liver; liver pathophysiology; physiology; signaling liver ... See more keywords
Wnt signaling in liver disease: emerging trends from a bibliometric perspective
Sign Up to like & getrecommendations! Published in 2019 at "PeerJ"
DOI: 10.7717/peerj.7073
Abstract: Background The Wnt signaling pathway, an evolutionarily conserved molecular transduction cascade, has been identified as playing a pivotal role in various physiological and pathological processes of the liver, including homeostasis, regeneration, cirrhosis, and hepatocellular carcinoma… read more here.
Keywords: wnt signaling; trends bibliometric; disease emerging; emerging trends ... See more keywords