Blocking TNF signaling may save lives in COVID-19 infection
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DOI: 10.1007/s11033-022-07166-x
Abstract: Global vaccination effort and better understanding of treatment strategies provided a ray of hope for improvement in COVID-19 pandemic, however, in many countries, the disease continues to collect its death toll. The major pathogenic mechanism… read more here.
Keywords: may save; save lives; tnf signaling; lives covid ... See more keywords
Abrogation of IFN-γ Signaling May not Worsen Sensitivity to PD-1/PD-L1 Blockade
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DOI: 10.3390/ijms21051806
Abstract: Programmed cell death protein 1 (PD-1)/PD-1 ligand 1 (PD-L1) blockade is a promising therapy for various cancer types, but most patients are still resistant. Therefore, a larger number of predictive biomarkers is necessary. In this… read more here.
Keywords: difngr1; blockade; ifn signaling; signaling may ... See more keywords