High-Content Screening Pipeline for Natural Products Targeting Oncogenic Signaling in Melanoma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c01154
Abstract: The incidence of melanoma, the most fatal dermatological cancer, has dramatically increased over the last few decades. Modern targeted therapy with kinase inhibitors induces potent clinical responses, but drug resistance quickly develops. Combination therapy improves… read more here.
Keywords: signaling melanoma; high content; melanoma; activity ... See more keywords
The Role of Calcium Signaling in Melanoma
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DOI: 10.3390/ijms23031010
Abstract: Calcium signaling plays important roles in physiological and pathological conditions, including cutaneous melanoma, the most lethal type of skin cancer. Intracellular calcium concentration ([Ca2+]i), cell membrane calcium channels, calcium related proteins (S100 family, E-cadherin, and… read more here.
Keywords: role calcium; calcium; calcium signaling; signaling melanoma ... See more keywords