Calcium signaling and molecular mechanisms underlying neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Cell calcium"
DOI: 10.1016/j.ceca.2017.06.008
Abstract: Calcium (Ca2+) is a ubiquitous second messenger that regulates various activities in eukaryotic cells. Especially important role calcium plays in excitable cells. Neurons require extremely precise spatial-temporal control of calcium-dependent processes because they regulate such… read more here.
Keywords: signaling molecular; molecular mechanisms; mechanisms underlying; underlying neurodegenerative ... See more keywords
Molecular mechanisms of FasL-mediated 'reverse-signaling'.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.08.010
Abstract: Effector lymphocytes, including NK and T cells, express FasL. Expression of Fas, the receptor for FasL in tumor cells, renders them susceptible to NK and T cell-mediated killing. The functional relevance of FasL in initiating… read more here.
Keywords: mediated reverse; signaling molecular; fasl mediated; molecular mechanisms ... See more keywords
Flux-Independent NMDAR Signaling: Molecular Mediators, Cellular Functions, and Complexities
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19123800
Abstract: The glutamate (Glu) N-methyl-d-aspartate (NMDA) receptor (NMDAR) plays a critical role in synaptic communication given mainly by its ionotropic function that permeates Ca2+. This in turn activates calmodulin that triggers CaMKII, MAPK, CREB, and PI3K… read more here.
Keywords: signaling molecular; independent nmdar; nmdar; flux independent ... See more keywords