Articles with "signaling pathways" as a keyword



Interactions between autophagy and phytohormone signaling pathways in plants

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Published in 2022 at "Febs Letters"

DOI: 10.1002/1873-3468.14355

Abstract: Autophagy is a conserved recycling process with important functions in plant growth, development, and stress responses. Phytohormones also play key roles in the regulation of some of the same processes. Increasing evidence indicates that a… read more here.

Keywords: autophagy phytohormone; phytohormone signaling; interactions autophagy; pathways plants ... See more keywords

TGF‐β transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 and ERK/Sp1 signaling pathways

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Published in 2018 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12162

Abstract: Transforming growth factor‐beta (TGF‐β) functions as a potent proliferation inhibitor and apoptosis inducer in the early stages of breast cancer, yet promotes cancer aggressiveness in the advanced stages. The dual effect of TGF‐β on cancer… read more here.

Keywords: signaling pathways; canonical smad3; breast cancer; tgf ... See more keywords

Single‐cell transcriptome analysis of male chicken germ cells reveals changes in signaling pathway‐related gene expression profiles during mitotic arrest

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Published in 2023 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13600

Abstract: Mitotic arrest is necessary for the embryonic development of germ cells, and thus, it is important to understand the signaling pathways that regulate mitotic arrest. Here, we investigated the signaling pathway dynamics of male embryonic… read more here.

Keywords: cell; arrest; mitotic arrest; germ cells ... See more keywords

Mimicking Cellular Signaling Pathways within Synthetic Multicompartment Vesicles with Triggered Enzyme Activity and Induced Ion Channel Recruitment

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Published in 2019 at "Advanced Functional Materials"

DOI: 10.1002/adfm.201904267

Abstract: Subcellular compartmentalization of cells, a defining characteristic of eukaryotes, is fundamental for the fine tuning of internal processes and the responding to external stimuli. Reproducing and controlling such compartmentalized hierarchical organization, responsiveness, and communication is… read more here.

Keywords: signaling pathways; cellular signaling; activity; multicompartment ... See more keywords

Isobavachalcone suppresses the TRIF‐dependent signaling pathway of Toll‐like receptors

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Published in 2021 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202100404

Abstract: Toll‐like receptors (TLRs) are integral membrane‐bound receptors that are central to innate and adaptive immune responses. They are known to activate a cascade of downstream signals to induce the secretion of inflammatory cytokines, chemokines, and… read more here.

Keywords: dependent signaling; trif dependent; signaling pathways; like receptors ... See more keywords

Colorectal Neoplasia Pathogenesis in Normal Appearing Colonic Mucosa ‐A Perspective With Focus on Eicosanoid Signaling Pathways

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Published in 2025 at "Cancer Medicine"

DOI: 10.1002/cam4.71168

Abstract: Colorectal cancer (CRC) is a major cause of cancer‐related mortality, especially in the Western world, and its incidence is expected to increase in the years to come. Prevention and early detection are key strategies to… read more here.

Keywords: signaling pathways; colorectal neoplasia; normal appearing; crn ... See more keywords

Delving Into lncRNA‐Mediated Regulation of Autophagy‐Associated Signaling Pathways in the Context of Breast Cancer

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Published in 2025 at "Cell Biology International"

DOI: 10.1002/cbin.12277

Abstract: Breast cancer is a multifaceted and prevalent malignancy, impacting a considerable proportion of women globally. Numerous signaling pathways intricately regulate cellular functions such as growth, proliferation, and survival. Among the various regulators, lncRNAs have emerged… read more here.

Keywords: cancer; breast cancer; signaling pathways; biology ... See more keywords

Signaling Pathways and Promising Small‐Molecule Therapeutic Agents for Ischemic Stroke

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Published in 2025 at "ChemMedChem"

DOI: 10.1002/cmdc.202400975

Abstract: Stroke is the second highest cause of death and leading cause of disability with high economic burden worldwide. The incidence of stroke is increasing faster and more prevalent for the global population over age 65.… read more here.

Keywords: signaling pathways; signalling pathways; ischemic stroke; stroke ... See more keywords
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Notch and Bmp signaling pathways act coordinately during the formation of the proepicardium

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Published in 2020 at "Developmental Dynamics"

DOI: 10.1002/dvdy.229

Abstract: The epicardium is the outer mesothelial layer of the heart. It encloses the myocardium and plays key roles in heart development and regeneration. It derives from the proepicardium (PE), cell clusters that appear in the… read more here.

Keywords: notch bmp; signaling pathways; bmp signaling; heart ... See more keywords
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Signaling pathways in mammalian preimplantation development: Linking cellular phenotypes to lineage decisions

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Published in 2017 at "Developmental Dynamics"

DOI: 10.1002/dvdy.24471

Abstract: The first stages of mammalian development, before implantation of the embryo in the maternal uterus, result in the establishment of three cell populations in the blastocyst: trophectoderm, epiblast, and primitive endoderm. These events involve only… read more here.

Keywords: signaling pathways; lineage; pathways mammalian; cellular phenotypes ... See more keywords

Vav family proteins constitute disparate branching points for distinct BCR signaling pathways

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Published in 2020 at "European Journal of Immunology"

DOI: 10.1002/eji.202048621

Abstract: Antigen recognition by B‐cell antigen receptors (BCRs) activates distinct intracellular signaling pathways that control the differentiation fate of activated B lymphocytes. BCR‐proximal signaling enzymes comprise protein tyrosine kinases, phosphatases, and plasma membrane lipid‐modifying enzymes, whose… read more here.

Keywords: signaling pathways; family; constitute disparate; proteins constitute ... See more keywords