APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model.
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DOI: 10.1016/j.celrep.2019.03.087
Abstract: Amyloid precursor protein (APP) and its metabolites play key roles in Alzheimer's disease (AD) pathophysiology. Whereas short amyloid-β (Aβ) peptides derived from APP are pathogenic, the APP holoprotein serves multiple purposes in the nervous system… read more here.
Keywords: app mediated; alzheimer disease; app; signaling prevents ... See more keywords