GPCR Signaling Regulation in Dictyostelium Chemotaxis.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_27
Abstract: GPCR signaling is the most prevailing molecular mechanism for detecting ambient signals in eukaryotes. Chemotactic cells use GPCR signaling to process chemical cues for directional migration over a broad concentration range and with high sensitivity.… read more here.
Keywords: regulation dictyostelium; signaling regulation; gpcr signaling; gpcr ... See more keywords
Chemokine Signaling and the Regulation of Bidirectional Leukocyte Migration in Interstitial Tissues.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.04.078
Abstract: Motile cells navigate through complex tissue environments that include both attractive and repulsive cues. In response to tissue wounding, neutrophils, primary cells of the innate immune response, exhibit bidirectional migration that is orchestrated by chemokines… read more here.
Keywords: chemokine signaling; interstitial tissues; signaling regulation; migration ... See more keywords
Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.03.028
Abstract: Intrinsically disordered proteins and regions (IDPs and IDRs) lack well-defined tertiary structures, yet carry out various important cellular functions, especially those associated with cell signaling and regulation. In eukaryotes, IDPs and IDRs contain the preferred… read more here.
Keywords: idps idrs; cell signaling; signaling regulation; cell ... See more keywords
Immunosuppression mechanism of entomopathogenic bacteria against Galleria mellonella larvae
Sign Up to like & getrecommendations! Published in 2019 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2019.03.021
Abstract: Abstract Entomopathogenic nematodes (EPNs) and their symbiotic bacteria play a great role in pest bio-control and therefore have been used widely in agricultural production. However, immunologic mechanisms on how they kill their hosts remain little… read more here.
Keywords: immunosuppression; immunity; signaling regulation; regulation humoral ... See more keywords
Central somatostatin signaling and regulation of food intake
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14178
Abstract: The discovery of somatostatin (SST) in the hypothalamus implicated the peptide in the inhibition of growth hormone release. However, as observed for numerous neuropeptides, SST was neither restricted to this one brain site nor to… read more here.
Keywords: sst; somatostatin signaling; central somatostatin; signaling regulation ... See more keywords
ERK1/2-RSK2 Signaling in Regulation of ERα -Mediated Responses.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac106
Abstract: Signaling via extracellular regulated kinase 1/2 (ERK1/2) and p90 ribosomal S6 kinase (RSK), a downstream effector, mediate numerous processes. For example, ERK1/2-RSK signaling is essential for estrogen homeostasis in the mammary gland and uterus to… read more here.
Keywords: erk1 rsk2; estrogen; rsk2 signaling; signaling regulation ... See more keywords
P2-type purinergic signaling in the regulation of pancreatic β-cell functional plasticity as a promising novel therapeutic approach for the treatment of type 2 diabetes?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1099152
Abstract: Diabetes Mellitus is a metabolic disorder characterized by a chronic hyperglycemia due to an impaired insulin secretion and a decreased in peripheral insulin sensitivity. This disease is a major public health problem due to it… read more here.
Keywords: type purinergic; signaling regulation; plasticity; purinergic signaling ... See more keywords