Notch Signaling is Required for Dendritic Cell Maturation and T Cell Expansion in Paracoccidioidomycosis
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DOI: 10.1007/s11046-018-0276-3
Abstract: The Notch signaling pathway participates in several cellular functional aspects. This signaling has an important role in targeting both DC maturation and DC-mediated T cell responses. Thus, it is essential to investigate the influence of… read more here.
Keywords: paracoccidioidomycosis; signaling required; notch signaling; maturation ... See more keywords
BDNF Release and Signaling are Required for the Antidepressant Actions of GLYX-13
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DOI: 10.1038/mp.2017.220
Abstract: Conventional antidepressant medications, which act on monoaminergic systems, display significant limitations, including a time lag of weeks to months and low rates of therapeutic efficacy. GLYX-13 is a novel glutamatergic compound that acts as an… read more here.
Keywords: signaling required; antidepressant actions; release; actions glyx ... See more keywords
Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function
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DOI: 10.1038/srep40820
Abstract: Prebiotics are non-digestible oligosaccharides that promote the growth of beneficial gut microbes, but it is unclear whether they also have direct effects on the intestinal mucosal barrier. Here we demonstrate two commercial prebiotics, inulin and… read more here.
Keywords: required dietary; barrier; dietary prebiotic; signaling required ... See more keywords
Notch effector recombination signal binding protein for immunoglobulin kappa J signaling is required for the initiation of endometrial stromal cell decidualization
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DOI: 10.1093/biolre/ioac140
Abstract: Abstract The Notch signaling pathway is required for reproductive success. This pathway activates its transcriptional effector, recombination signal binding protein for immunoglobulin kappa J (Rbpj), to induce transcription of its target genes. This signaling pathway… read more here.
Keywords: decidualization; notch effector; required initiation; signaling required ... See more keywords