Signaling Systems in Oral Bacteria.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-28524-1_3
Abstract: The supra- and subgingival plaque biofilm communities of plaque are composed of hundreds of different microbes. These communities are spatially and temporally structured, largely due to cell-cell communications that coordinate synergistic interactions, and intracellular signaling… read more here.
Keywords: community; oral bacteria; systems oral; biology ... See more keywords
Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.10.010
Abstract: Summary The peptidergic system is the most abundant network of ligand-receptor-mediated signaling in humans. However, the physiological roles remain elusive for numerous peptides and more than 100 G protein-coupled receptors (GPCRs). Here we report the… read more here.
Keywords: human signaling; discovery human; protein coupled; coupled receptors ... See more keywords
Bioinspired Design of Artificial Signaling Systems.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00368
Abstract: Natural systems use weak interactions and avidity effects to give biological systems high specificity and signal-to-noise ratios. Here we describe design principles for engineering fusion proteins that target therapeutic fusion proteins to membrane-bound signaling receptors… read more here.
Keywords: signaling systems; artificial signaling; design artificial; affinity ... See more keywords
Connecting Artificial Proteolytic and Electrochemical Signaling Systems with Caged Messenger Peptides.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.1c00845
Abstract: Enzymatic polypeptide proteolysis is a widespread and powerful biological control mechanism. Over the last few years, substantial progress has been made in creating artificial proteolytic systems where an input of choice modulates the protease activity… read more here.
Keywords: connecting artificial; electrochemical signaling; systems caged; proteolytic electrochemical ... See more keywords
Multiple factors affect the evolution of repertoire size across birds
Sign Up to like & getrecommendations! Published in 2021 at "Behavioral Ecology"
DOI: 10.1093/beheco/araa139
Abstract: Changes in signaling repertoires across species allow for insight into the macroevolutionary forces that control signaling systems. Signaling systems are theorized to be affected by both the social and ecological environments of species. With respect… read more here.
Keywords: repertoire; evolution; ecology; repertoire size ... See more keywords
The role of red coloration and song in peacock spider courtship: insights into complex signaling systems
Sign Up to like & getrecommendations! Published in 2018 at "Behavioral Ecology"
DOI: 10.1093/beheco/ary128
Abstract: Author(s): Girard, MB; Kasumovic, MM; Elias, DO | Abstract: © 2018 The Author(s). Research on animal signaling enhances our understanding of links between sensory processing, decision making, behavior, and evolution. Studies of sexually-selected signals may… read more here.
Keywords: red coloration; peacock; courtship; complex signaling ... See more keywords
Two enhancer binding proteins activate σ54-dependent transcription of a quorum regulatory RNA in a bacterial symbiont
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.04.27.489697
Abstract: To colonize a host, bacteria depend on an ensemble of signaling systems to convert information about the various environments encountered within the host into specific cellular activities. How these signaling systems coordinate transitions between cellular… read more here.
Keywords: signaling systems; bacterial symbiont; transcription; two enhancer ... See more keywords
Deregulation of Ca2+-Signaling Systems in White Adipocytes, Manifested as the Loss of Rhythmic Activity, Underlies the Development of Multiple Hormonal Resistance at Obesity and Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22105109
Abstract: Various types of cells demonstrate ubiquitous rhythmicity registered as simple and complex Ca2+-oscillations, spikes, waves, and triggering phenomena mediated by G-protein and tyrosine kinase coupled receptors. Phospholipase C/IP3-receptors (PLC/IP3R) and endothelial NO-synthase/Ryanodine receptors (NOS/RyR)–dependent Ca2+… read more here.
Keywords: ca2 signaling; hormonal resistance; rhythmicity; obesity ... See more keywords