Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
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DOI: 10.1038/s41467-021-23653-4
Abstract: Generating properly differentiated embryonic structures in vitro from pluripotent stem cells remains a challenge. Here we show that instruction of aggregates of mouse embryonic stem cells with an experimentally engineered morphogen signalling centre, that functions… read more here.
Keywords: signalling centre; mammalian embryo; morphogen signalling; stem ... See more keywords