Scaffold-mediated gating of Cdc42 signalling flux
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DOI: 10.7554/elife.25257
Abstract: Scaffold proteins modulate signalling pathway activity spatially and temporally. In budding yeast, the scaffold Bem1 contributes to polarity axis establishment by regulating the GTPase Cdc42. Although different models have been proposed for Bem1 function, there… read more here.
Keywords: cdc42; signalling flux; scaffold mediated; gef activity ... See more keywords