SGK1 is a signalling hub that controls protein synthesis and proliferation in endothelial cells
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DOI: 10.1002/1873-3468.13901
Abstract: BMP9 is a cytokine involved in the maturation phase of the angiogenic process that signals through its serine/threonine receptor ALK1 and its coreceptor endoglin. In this paper, we explain how BMP9 directs the regulation of… read more here.
Keywords: proliferation; hub controls; protein synthesis; signalling hub ... See more keywords
SK2 channels set a signalling hub bolstering CAF-triggered tumourigenic processes in pancreatic cancer
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DOI: 10.1136/gutjnl-2021-326610
Abstract: Objective Intercellular communication within pancreatic ductal adenocarcinoma (PDAC) dramatically contributes to metastatic processes. The underlying mechanisms are poorly understood, resulting in a lack of targeted therapy to counteract stromal-induced cancer cell aggressiveness. Here, we investigated… read more here.
Keywords: caf; pancreatic cancer; signalling hub; sk2 channels ... See more keywords