Articles with "signalling insights" as a keyword



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Insights into ligand stimulation effects on gastro-intestinal stromal tumors signalling.

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Published in 2017 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2016.10.009

Abstract: Mutations in KIT or PDGFRA are responsible for >85% of gastrointestinal stromal tumors. The introduction of imatinib in the GIST therapy scheme revolutionized the patient outcome. Unfortunately, the therapy allows the disease stabilization instead of… read more here.

Keywords: kinase activity; stromal tumors; gist; kit mutants ... See more keywords
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The evolution of neuropeptide signalling: insights from echinoderms

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Published in 2017 at "Briefings in Functional Genomics"

DOI: 10.1093/bfgp/elx005

Abstract: Abstract Neuropeptides are evolutionarily ancient mediators of neuronal signalling that regulate a wide range of physiological processes and behaviours in animals. Neuropeptide signalling has been investigated extensively in vertebrates and protostomian invertebrates, which include the… read more here.

Keywords: insights echinoderms; hormone; evolution neuropeptide; neuropeptide signalling ... See more keywords