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Published in 2017 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2016.10.009
Abstract: Mutations in KIT or PDGFRA are responsible for >85% of gastrointestinal stromal tumors. The introduction of imatinib in the GIST therapy scheme revolutionized the patient outcome. Unfortunately, the therapy allows the disease stabilization instead of…
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Keywords:
kinase activity;
stromal tumors;
gist;
kit mutants ... See more keywords
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Published in 2017 at "Briefings in Functional Genomics"
DOI: 10.1093/bfgp/elx005
Abstract: Abstract Neuropeptides are evolutionarily ancient mediators of neuronal signalling that regulate a wide range of physiological processes and behaviours in animals. Neuropeptide signalling has been investigated extensively in vertebrates and protostomian invertebrates, which include the…
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Keywords:
insights echinoderms;
hormone;
evolution neuropeptide;
neuropeptide signalling ... See more keywords