Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of hepatocellular carcinoma
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DOI: 10.7554/elife.76294
Abstract: Quantitative differences in signal transduction are to date an understudied feature of tumour heterogeneity. The MAPK Erk pathway, which is activated in a large proportion of human tumours, is a prototypic example of distinct cell… read more here.
Keywords: hepatocellular carcinoma; signalling intensity; intensity; mapk signalling ... See more keywords