Articles with "signalling molecules" as a keyword



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Lysophospholipid Signalling and the Tumour Microenvironment.

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Published in 2021 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-47189-7_8

Abstract: Homeostasis is the key to survival. This is as true for the tumour cell as it is for the normal host cell. Tumour cells and normal host cells constantly interact with each other, and the… read more here.

Keywords: microenvironment; tumour cells; host; signalling molecules ... See more keywords
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Recent progress on signalling molecules of coral-associated microorganisms

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Published in 2019 at "Science China Earth Sciences"

DOI: 10.1007/s11430-018-9332-1

Abstract: Coral reefs have high primary productivity and are one of the most important ecosystems in the ocean. However, the health and stability of coral reefs are constantly threatened by climate change and human activities. The… read more here.

Keywords: coral associated; signalling molecules; recent progress; coral reefs ... See more keywords
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Detailed expression profile of the six Glypicans and their modifying enzyme, Notum during chick limb and feather development.

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Published in 2017 at "Gene"

DOI: 10.1016/j.gene.2017.02.012

Abstract: The development of vertebrate appendages, especially the limb and feather buds are orchestrated by numerous secreted signalling molecules including Sonic Hedgehog, Bone Morphogenetic Proteins, Fibroblast Growth Factors and Wnts. These proteins coordinate the growth and… read more here.

Keywords: limb feather; expression; signalling molecules; chick limb ... See more keywords
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Extracellular nucleotides and nucleosides as signalling molecules.

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Published in 2019 at "Immunology letters"

DOI: 10.1016/j.imlet.2018.11.006

Abstract: Extracellular nucleotides, mainly ATP, but also ADP, UTP, UDP and UDP-sugars, adenosine, and adenine base participate in the "purinergic signalling" pathway, an ubiquitous system of cell-to-cell communication. Fundamental pathophysiological processes such as tissue homeostasis, wound… read more here.

Keywords: purinergic signalling; extracellular nucleotides; nucleotides nucleosides; signalling molecules ... See more keywords
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Antiviral activity of bacterial TIR domains via immune signalling molecules.

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Published in 2021 at "Nature"

DOI: 10.1038/s41586-021-04098-7

Abstract: The Toll/interleukin-1 receptor (TIR) domain is a canonical component of animal and plant immune systems1,2. In plants, intracellular pathogen sensing by immune receptors triggers their TIR domains to generate a molecule that is a variant… read more here.

Keywords: antiviral activity; tir domain; bacterial tir; tir domains ... See more keywords
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ROS and RNS: key signalling molecules in plants

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Published in 2018 at "Journal of Experimental Botany"

DOI: 10.1093/jxb/ery198

Abstract: Both reactive oxygen species (ROS) and reactive nitrogen species (RNS) are important signals in plants and key regulators of a variety of processes including metabolism, growth and development, response to abiotic and biotic stresses, solute… read more here.

Keywords: botany; ros rns; molecules plants; rns key ... See more keywords
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Phosphorylation of intracellular signalling molecules in peripheral blood cells from patients with psoriasis on originator or biosimilar infliximab

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Published in 2018 at "British Journal of Dermatology"

DOI: 10.1111/bjd.16269

Abstract: Psoriasis vulgaris is a chronic, inflammatory skin disease characterized by a dysregulated immune response and it is associated with substantial systemic comorbidities. Biological drugs such as tumour necrosis factor (TNF)‐α inhibitors can ameliorate the disease… read more here.

Keywords: phosphorylation intracellular; originator; signalling molecules; molecules peripheral ... See more keywords
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Sex‐specific differences in cardiovascular and metabolic hormones with integrated signalling in the paraventricular nucleus of the hypothalamus

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Published in 2017 at "Experimental Physiology"

DOI: 10.1113/ep086436

Abstract: What is the topic of this review? We describe roles of crucial signalling molecules in the paraventricular nucleus of the hypothalamus and highlight recent data suggesting sex‐specific changes in the expression of crucial signalling molecules… read more here.

Keywords: cardiovascular metabolic; paraventricular nucleus; sex specific; sex ... See more keywords
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Ketone Bodies as Metabolites and Signalling Molecules at the Crossroad between Inflammation and Epigenetic Control of Cardiometabolic Disorders

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232314564

Abstract: For many years, it has been clear that a Western diet rich in saturated fats and sugars promotes an inflammatory environment predisposing a person to chronic cardiometabolic diseases. In parallel, the emergence of ketogenic diets,… read more here.

Keywords: inflammation; bodies metabolites; ketone bodies; signalling molecules ... See more keywords