Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: implications for drug discovery.
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DOI: 10.1111/bph.15700
Abstract: BACKGROUND AND PURPOSE The pituitary adenylate cyclase-activating peptide (PACAP) peptide family is of clinical interest for the treatment of migraine. These peptides activate three different PACAP-responsive class B G protein-coupled receptors: the PAC1 , VPAC1… read more here.
Keywords: pacap responsive; pacap; signalling profiles; pharmacology ... See more keywords