Development and Validation of an Individualized Immune Prognostic Signature in Early-Stage Nonsquamous Non–Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.1609
Abstract: Importance The prevalence of early-stage non–small cell lung cancer (NSCLC) is expected to increase with recent implementation of annual screening programs. Reliable prognostic biomarkers are needed to identify patients at a high risk for recurrence… read more here.
Keywords: validation; nonsquamous nsclc; early stage; signature ... See more keywords
A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy‐treated head and neck squamous cell carcinoma (HNSCC)
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DOI: 10.1002/1878-0261.12388
Abstract: Previously, we have shown that copy number gain of the chromosomal band 16q24.3 is associated with impaired clinical outcome of radiotherapy‐treated head and neck squamous cell carcinoma (HNSCC) patients. We set out to identify a… read more here.
Keywords: cell; chemo therapy; hnscc; signature ... See more keywords
An autophagy‐related long non‐coding RNA signature for glioma
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DOI: 10.1002/2211-5463.12601
Abstract: Glioma is one of the most common types of malignant primary central nervous system tumor, and prognosis for this disease is poor. As autophagic drugs have been reported to induce glioma cell death, we investigated… read more here.
Keywords: autophagy related; risk; glioma; as1 ... See more keywords
A prognostic signature based on three non‐coding RNAs for prediction of the overall survival of glioma patients
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DOI: 10.1002/2211-5463.12602
Abstract: Recent studies have identified certain non‐coding RNAs (ncRNAs) as biomarkers of disease progression. Glioma is the most common primary intracranial cancer, with high mortality. Here, we developed a prognostic signature for prediction of overall survival… read more here.
Keywords: glioma patients; risk; glioma; non coding ... See more keywords
A three‐lncRNA expression signature associated with the prognosis of gastric cancer patients
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DOI: 10.1002/cam4.1047
Abstract: Long noncoding RNAs (lncRNAs) have emerged as essential players in gene regulation. An ever‐increasing number of lncRNAs has been found to be associated with the biogenesis and prognosis of gastric cancer (GC). We aimed to… read more here.
Keywords: lncrna expression; prognosis; expression signature; expression ... See more keywords
Identification of a novel gene pairs signature in the prognosis of gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1303
Abstract: Current prognostic signatures need to be improved in identifying high‐risk patients of gastric cancer (GC). Thus, we aimed to develop a reliable prognostic signature that could assess the prognosis risk in GC patients. Two microarray… read more here.
Keywords: risk; prognosis; signature; cancer ... See more keywords
Development and validation of an individualized diagnostic signature in thyroid cancer
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DOI: 10.1002/cam4.1397
Abstract: New molecular signatures are needed to improve the diagnosis of thyroid cancer (TC) and avoid unnecessary surgeries. In this study, we aimed to develop a robust and individualized diagnostic signature in TC. Gene expression profiles… read more here.
Keywords: individualized diagnostic; thyroid cancer; diagnostic signature; signature ... See more keywords
Bioinformatic profiling identifies a platinum‐resistant–related risk signature for ovarian cancer
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DOI: 10.1002/cam4.2692
Abstract: Most high‐grade serous ovarian cancer (HGSOC) patients develop resistance to platinum‐based chemotherapy and recur. Many biomarkers related to the survival and prognosis of drug‐resistant patients have been delved by mining databases; however, the prediction effect… read more here.
Keywords: risk; risk score; resistance; signature ... See more keywords
MET transcriptional regulator/serine peptidase inhibitor kunitz type 1 panel operating through HGF/c‐MET axis as a prognostic signature in pan‐cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3834
Abstract: Dysregulations in transcription factors (TFs) and their genetic products play important roles in tumorigenesis, tumor progression and metastasis. However, prognostic value of the transcriptional regulatory networks in different cancers has not been investigated in depth.… read more here.
Keywords: met transcriptional; hgf met; signature; cancer ... See more keywords
A B‐Raf V600E gene signature for melanoma predicts prognosis and reveals sensitivity to targeted therapies
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DOI: 10.1002/cam4.4491
Abstract: B‐Raf V600E mutations account for about half of all skin cutaneous melanoma cases, and patients with this mutation are sensitive to BRAF inhibitors. However, aberrations in other genes in the MAPK/ERK pathway may cascade a… read more here.
Keywords: prognosis; sensitivity; melanoma; signature ... See more keywords
Clinical and molecular assessment of an onco‐immune signature with prognostic significance in patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4568
Abstract: Understanding the complex tumor microenvironment is key to the development of personalized therapies for the treatment of cancer including colorectal cancer (CRC). In the past decade, significant advances in the field of immunotherapy have changed… read more here.
Keywords: signature; crc; colorectal cancer; gene ... See more keywords