Differential Phospho‐Signatures in Blood Cells Identify LRRK2 G2019S Carriers in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28927
Abstract: The clinicopathological phenotype of G2019S LRRK2‐associated Parkinson's disease (L2PD) is similar to idiopathic Parkinson's disease (iPD), and G2019S LRRK2 nonmanifesting carriers (L2NMCs) are at increased risk for development of PD. With various therapeutic strategies in… read more here.
Keywords: signatures blood; phospho signatures; differential phospho; parkinson disease ... See more keywords
Thermodynamic Signatures of Blood Plasma Proteome in Neurodegenerative Pathologies
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DOI: 10.3390/ijms24010789
Abstract: Discovery of diagnostic biomarkers for age-related neurodegenerative pathologies (NDDs) is essential for accurate diagnosis, following disease progression and drug development. Blood plasma and blood cells are important peripheral sources for NDDs’ biomarkers that, although present… read more here.
Keywords: thermodynamic signatures; signatures blood; plasma proteome; neurodegenerative pathologies ... See more keywords