Articles with "signatures tau" as a keyword



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Transcriptional Signatures of Tau and Amyloid Neuropathology

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Published in 2020 at "Cell Reports"

DOI: 10.1016/j.celrep.2020.01.063

Abstract: Summary Alzheimer’s disease (AD) is associated with the intracellular aggregation of hyperphosphorylated tau and the accumulation of β-amyloid in the neocortex. We use transgenic mice harboring human tau (rTg4510) and amyloid precursor protein (J20) mutations… read more here.

Keywords: transcriptional signatures; signatures tau; neuropathology; pathology ... See more keywords