The evaluation and management of monoclonal gammopathy of renal significance and monoclonal gammopathy of neurological significance
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26155
Abstract: Despite the benign nature of monoclonal gammopathy of undetermined significance (MGUS), mounting data are associating MGUS with the development of organ dysfunction, specifically monoclonal gammopathy of renal significance (MGRS) and monoclonal gammopathy of neurological significance… read more here.
Keywords: monoclonal gammopathy; gammopathy renal; significance; neurological significance ... See more keywords
Assessing risk factors with information beyond P value thresholds: Statistical significance does not equal clinical importance
Sign Up to like & getrecommendations! Published in 2020 at "Cancer"
DOI: 10.1002/cncr.33369
Abstract: SELECTING PREDICTORS OF INTEREST BASED ON STATISTICAL SIGNIFICANCE Observational studies published in Cancer may seek to identify risk factors for an outcome of interest by using multivariable models or multiple univariable models if the sample… read more here.
Keywords: statistical significance; assessing risk; value; risk factors ... See more keywords
When significance becomes insignificant: Effect sizes and their uncertainties in Bayesian and frequentist frameworks as an alternative approach when analyzing ecotoxicological data.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4127
Abstract: Bayesian methods and frequentist confidence intervals are proposed as an alternative approach in ecotoxicology, emphasizing effect sizes and associated (un)certainties to judge the biological relevance of effects instead of basing decisions on p values. These… read more here.
Keywords: frequentist; effect; alternative approach; significance ... See more keywords
Estimation of a significance threshold for epigenome‐wide association studies
Sign Up to like & getrecommendations! Published in 2018 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22086
Abstract: Epigenome‐wide association studies (EWAS) are designed to characterise population‐level epigenetic differences across the genome and link them to disease. Most commonly, they assess DNA‐methylation status at cytosine‐guanine dinucleotide (CpG) sites, using platforms such as the… read more here.
Keywords: association studies; significance threshold; significance; epigenome wide ... See more keywords
A simple and accurate method to determine genomewide significance for association tests in sequencing studies
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22183
Abstract: Whole‐exome sequencing (WES) and whole‐genome sequencing (WGS) studies are underway to investigate the impact of genetic variants on complex diseases and traits. It is customary to perform single‐variant association tests for common variants and region‐based… read more here.
Keywords: simple accurate; association tests; genomewide significance; significance ... See more keywords
Quantification of behavioral data with effect sizes and statistical significance tests.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied behavior analysis"
DOI: 10.1002/jaba.938
Abstract: This article describes the use of statistical significance tests and distance-based effect sizes with behavioral data from single case experimental designs (SCEDs). Such data often are interpreted only with visual analysis. However, a growing movement… read more here.
Keywords: significance tests; statistical significance; significance; behavioral data ... See more keywords
The study of routine laboratory factors in children with mycoplasma pneumoniae pneumonia: serum uric acid may have anti-inflammatory effect.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24026
Abstract: BACKGROUND High uric acid levels are a risk factor for cardiovascular disorders, and metabolic diseases; however, the role of serum uric acid (sUA) during the mycoplasma pneumoniae pneumonia (MPP) of children is poorly known. This… read more here.
Keywords: mpp; uric acid; study; non mpp ... See more keywords
Views of Israeli healthcare professionals regarding communication of genetic variants of uncertain significance to patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Genetic Counseling"
DOI: 10.1002/jgc4.1560
Abstract: While genomic medicine is becoming an important part of patient care with an ever‐increasing diagnostic yield, communicating variants of uncertain clinical significance (VUSs) remains a major challenge. We draw on qualitative analysis of semi‐structured interviews… read more here.
Keywords: communication; significance; israeli healthcare; variants uncertain ... See more keywords
Pathophysiological Significance of Store-Operated Calcium Entry in Cardiovascular and Skeletal Muscle Disorders and Angiogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-12457-1_19
Abstract: Store-Operated Ca2+ Entry (SOCE) is an important Ca2+ influx pathway expressed by several excitable and non-excitable cell types. SOCE is recognized as relevant signaling pathway not only for physiological process, but also for its involvement… read more here.
Keywords: skeletal muscle; store operated; cardiovascular skeletal; significance ... See more keywords
Predictive significance of tissue hypoperfusion markers in different shock types in low income countries
Sign Up to like & getrecommendations! Published in 2019 at "Medizinische Klinik - Intensivmedizin und Notfallmedizin"
DOI: 10.1007/s00063-019-0592-5
Abstract: The most common condition that brings patients to the medical intensive care unit (MICU) is hemodynamic instability, accompanied by tissue hypoperfusion. In order to make easier and quicker diagnosis of this syndrome marker tissue hypoperfusion… read more here.
Keywords: die; der; tissue hypoperfusion; significance ... See more keywords
Sociodemographic variation in foraging behavior and the adaptive significance of worker production in the facultatively social small carpenter bee, Ceratina calcarata
Sign Up to like & getrecommendations! Published in 2017 at "Behavioral Ecology and Sociobiology"
DOI: 10.1007/s00265-017-2365-6
Abstract: Provisioning for young offspring is an archetypical form of parental investment. Ceratina calcarata bees provide extended maternal care to their young and demonstrate an unusual strategy of dual-phase pollen provisioning. Most bees first gather provisions… read more here.
Keywords: ceratina calcarata; investment; foraging behavior; significance ... See more keywords